Description

2,4-Difluoro-Benzoic Acid tert-Butyl Ester is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially those requiring a difluorobenzoyl moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with unique electronic and optical properties.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to introduce the 2,4-difluorobenzoate group into more complex molecular architectures.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	2,4-Difluoro-Benzoic Acid tert-Butyl Ester
CAS No.	500353-15-1
Molecular Formula	C11H12F2O2
Molecular Weight	214.21 g/mol
Synonyms	tert-Butyl 2,4-difluorobenzoate; 2,4-Difluorobenzoic Acid tert-Butyl Ester; Benzoic acid, 2,4-difluoro-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 2,4-difluorobenzoate; 2,4-Difluorobenzoic Acid 1,1-Dimethylethyl Ester; 2,4-DFBA tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-Benzoic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and sources of ignition. Due to its sensitivity to hydrolysis and strong alkali, ensure the container is kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.