Description

3-Azido-1,4-Dideoxy-1,4-Dihydro-1,4-Dioxorifamycin is a chemically modified derivative of the rifamycin class of antibiotics, specifically designed for research and development applications. This compound matters as a key synthetic intermediate or a potential precursor for developing novel antimicrobial agents and exploring new mechanisms of action. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on antibiotic discovery and chemical biology.

Application

• Pharmaceutical Research Intermediate: Serves as a crucial building block in the synthesis of novel rifamycin analogs and next-generation antibiotics.
• Antimicrobial Mechanism Studies: Used in biochemical and microbiological research to investigate structure-activity relationships (SAR) and bacterial RNA polymerase inhibition.
• Chemical Biology Probe: Utilized in the development of photoaffinity labeling agents or other chemical probes due to the reactive azido group.
• Medicinal Chemistry Development: Acts as a starting material for the design and optimization of new chemical entities with potential therapeutic activity against resistant bacterial strains.
• Academic Research: Employed in university and institutional labs for studies in organic synthesis, antibiotic resistance, and drug discovery projects.

Basic Information

Product Name	3-Azido-1,4-Dideoxy-1,4-Dihydro-1,4-Dioxorifamycin
CAS No.	59886-91-8
Molecular Formula	C37H45N3O11
Molecular Weight	707.77 g/mol
Synonyms	3-Azidorifamycin S; 3-Azido-1,4-dideoxy-1,4-dihydro-1,4-dioxorifamycin S; 3-Azido-1,4-dideoxy-1,4-dihydro-1,4-dioxo-rifamycin; 3-Azido-1,4-dideoxy-1,4-dihydro-1,4-dioxorifamycin SV; 3-Azidorifamycin; Rifamycin S, 3-azido-1,4-dideoxy-1,4-dihydro-1,4-dioxo-; 3-Azido-1,4-dideoxy-1,4-dihydro-1,4-dioxorifamycin (non-preferred IUPAC)
EINECS	Contact for details

Quality Control

Our 3-Azido-1,4-Dideoxy-1,4-Dihydro-1,4-Dioxorifamycin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Reddish-brown to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.