Description

Piperacillin Sodium Salt is a semi-synthetic, broad-spectrum β-lactam antibiotic belonging to the ureidopenicillin class. It is valued for its potent activity against a wide range of Gram-negative and Gram-positive bacteria, including Pseudomonas aeruginosa. This compound is essential for pharmaceutical manufacturers and research institutions involved in developing and producing injectable antibiotic formulations. Its sodium salt form enhances solubility, making it suitable for parenteral administration.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the manufacture of injectable antibiotic drugs.
• Combination Therapy: Used in fixed-dose combination products, most notably with tazobactam, to overcome bacterial β-lactamase resistance.
• Hospital-Use Pharmaceuticals: Formulated for intravenous or intramuscular injection to treat serious infections like sepsis, pneumonia, and intra-abdominal infections.
• Microbiological Research: Serves as a reference standard and selective agent in antimicrobial susceptibility testing and bacteriological studies.
• Veterinary Medicine: Employed in the development of treatments for bacterial infections in animals.
• Pharmaceutical Development: Used in stability studies, formulation research, and the development of generic drug products.

Basic Information

Product Name	Piperacillin Sodium Salt
CAS No.	59703-84-3
Molecular Formula	C23H26N5NaO7S
Molecular Weight	539.54 g/mol
Synonyms	Piperacillin Sodium; Sodium Piperacillin; Piperacillin Na; (2S,5R,6R)-6-[[(2R)-2-[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt; Pipril Sodium; Pentcillin Sodium; T-1220 Sodium Salt; Avocin Sodium
EINECS	Contact for details

Quality Control

Our Piperacillin Sodium Salt is manufactured under strict quality management systems. It is typically tested to meet high-purity standards relevant for pharmaceutical applications, with specifications aligning with pharmacopeial monographs. Certificates of Analysis (COA) documenting identity, purity, potency, and related substances are provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C) or as specified. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
pH (10% solution)	5.5 - 7.5
Related Substances (HPLC)	Total impurities ≤ 3.0%
Bacterial Endotoxins	< 0.05 EU/mg
Sterility (if required)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.