Description

2-Bromo Carbenicillin Disodium Salt is a chemically modified derivative of the broad-spectrum penicillin antibiotic carbenicillin. This compound is primarily valued as a key intermediate in the research and development of novel β-lactam antibiotics and enzyme inhibitors. It serves the pharmaceutical, biotechnology, and academic research sectors, where it is utilized in synthetic chemistry, structure-activity relationship (SAR) studies, and biochemical research.

Application

• Pharmaceutical Intermediate: Critical starting material or building block in the synthesis of advanced β-lactam antibiotic analogs and prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving β-lactamases and penicillin-binding proteins (PBPs).
• Structure-Activity Relationship (SAR) Studies: The bromo substituent provides a reactive handle for further chemical modifications, aiding in the exploration of new antibiotic scaffolds.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Microbiology Research: Employed in studies investigating bacterial resistance mechanisms and the development of combination therapies.

Basic Information

Product Name	2-Bromo Carbenicillin Disodium Salt
CAS No.	59530-63-1
Molecular Formula	C17H16BrN2Na2O6S
Molecular Weight	493.27 g/mol
Synonyms	2-Bromocarbenicillin Disodium; Disodium (2S,5R,6R)-6-[(2R)-2-Bromo-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; 2-Bromo-α-phenylacetamido-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Disodium Salt; BRL 2036 (Disodium Salt); α-Bromophenylacetamidopenicillanic Acid Disodium Salt; 2-Bromo-α-phenylacetamidopenicillanic Acid Disodium Salt
EINECS	Contact for details

Quality Control

Our 2-Bromo Carbenicillin Disodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or cGMP intermediate requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and potency. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 0.25 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.