Description

Berninamycin A CAS NO 58798-97-3 is a thiopeptide antibiotic belonging to the berninamycin family, characterized by its complex macrocyclic structure. This compound is of significant interest in pharmaceutical research and development due to its potent antibacterial activity, particularly against Gram-positive bacteria. It serves as a critical reference standard and starting material for researchers in antimicrobial discovery, medicinal chemistry, and biochemistry.

Application

• Pharmaceutical Reference Standard: Used as a high-purity benchmark for quality control, method development, and validation in analytical laboratories.
• Antimicrobial Research: Serves as a lead compound or tool for studying mechanisms of action against resistant bacterial strains and for structure-activity relationship (SAR) studies.
• Biochemical Research: Employed in studies investigating bacterial protein synthesis inhibition, specifically targeting the ribosome.
• Medicinal Chemistry: Acts as a core structure for the semi-synthesis of novel antibiotic derivatives and analogs.
• Microbiology Studies: Utilized in in-vitro assays to determine minimum inhibitory concentrations (MICs) and evaluate antibacterial efficacy.

Basic Information

Product Name	Berninamycin A
CAS No.	58798-97-3
Molecular Formula	C52H64N14O16S6
Molecular Weight	1301.5 g/mol
Synonyms	Berninamycin A; Antibiotic B-58941; NSC 326450; Thiopeptide B-58941; Berninamycin; B-58941; Antibiotic B58941
EINECS	Contact for details

Quality Control

Our Berninamycin A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is accompanied by comprehensive analytical data, including HPLC chromatograms for purity assessment. Certificates of Analysis (COA) detailing identity, purity, and related substances are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.