Description

Apalcillin Sodium CAS NO 58795-03-2 is a semi-synthetic penicillin derivative belonging to the acylureidopenicillin class of β-lactam antibiotics. This compound is valued for its extended spectrum of antibacterial activity, particularly against Gram-negative organisms including Pseudomonas aeruginosa. It is primarily utilized in pharmaceutical research and development for the formulation of injectable antibiotic preparations, serving the needs of active pharmaceutical ingredient (API) manufacturers and clinical research organizations globally.

Application

• Pharmaceutical API Manufacturing: Serves as the active pharmaceutical ingredient in the formulation of injectable antibiotic drugs.
• Clinical Research & Development: Used in preclinical and clinical studies to evaluate efficacy against resistant bacterial strains.
• Microbiological Research: Employed as a reference standard in studies of β-lactamase stability and bacterial resistance mechanisms.
• Veterinary Medicine: Potential application in developing treatments for bacterial infections in animals.
• Antibiotic Susceptibility Testing: Used to prepare discs or solutions for in-vitro antimicrobial susceptibility testing (AST).

Basic Information

Product Name	Apalcillin Sodium
CAS No.	58795-03-2
Molecular Formula	C25H22N5NaO6S
Molecular Weight	543.53 g/mol
Synonyms	Apalcillin Sodium Salt; PC-904; (2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Sodium Salt; Sodium Apalcillin; Apalcillinum Natricum; BRL-44154; Apalcillin Na
EINECS	Contact for details

Quality Control

Our Apalcillin Sodium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including identification, purity assay, and impurity profiling to ensure it meets high-grade pharmaceutical standards. A Certificate of Analysis (COA) detailing specific results for appearance, assay, related substances, residual solvents, and microbiological quality is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
pH (10% solution)	5.5 - 7.5
Bacterial Endotoxins	< 0.25 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.