Description

T-Butyl 4-Fluorobenzoate is a high-purity organic building block and ester derivative of 4-fluorobenzoic acid. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, particularly in pharmaceutical and agrochemical research and development. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorobenzoate moiety is required.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material in the development of fluorinated organic electronic materials and liquid crystal compounds.
• Polymer Modification: Employed as a monomer or modifying agent to introduce fluorinated phenyl groups into specialty polymers, enhancing their properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, for C-C and C-N bond formation.
• Protecting Group Strategy: The tert-butyl ester group can be used as a protecting group for carboxylic acids in multi-step synthetic sequences.

Basic Information

Product Name	T-Butyl 4-Fluorobenzoate
CAS No.	58656-98-7
Molecular Formula	C11H13FO2
Molecular Weight	196.22 g/mol
Synonyms	4-Fluorobenzoic Acid tert-Butyl Ester; tert-Butyl 4-Fluorobenzoate; p-Fluorobenzoic Acid tert-Butyl Ester; Benzoic acid, 4-fluoro-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-fluorobenzoate; t-Butyl p-fluorobenzoate; TB4FB
EINECS	Contact for details

Quality Control

Our T-Butyl 4-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.