Description

1,3,6-Trisulfonylpyrene 8-Isothiocyanate is a highly functionalized, multi-sulfonated pyrene derivative bearing a reactive isothiocyanate group. This compound is valued for its ability to act as a versatile labeling and cross-linking agent, particularly in aqueous and biological systems due to its sulfonate groups enhancing water solubility. It is primarily needed by researchers and manufacturers in the fields of advanced material science, bioconjugation, and the development of fluorescent probes and sensors.

Application

• Bioconjugation and Protein Labeling: The reactive isothiocyanate group allows for covalent attachment to amine groups on proteins, antibodies, or other biomolecules, while the sulfonate groups improve solubility in aqueous buffers.
• Fluorescent Probe Synthesis: Serves as a key precursor or core structure for creating water-soluble, sulfonated fluorescent dyes and sensors with pyrene-based emission properties.
• Material Science Functionalization: Used to introduce sulfonate and reactive sites onto surfaces, nanoparticles, or polymers to modify hydrophilicity, charge, and bio-recognition capabilities.
• Cross-linking Agent: Employed in the preparation of hydrogels, polymer networks, or immobilized enzyme systems where stable covalent linkages are required.
• Diagnostic Reagent Development: Potential use in the formulation of reagents for immunoassays or histochemical staining due to its labeling functionality.
• Research Chemical: Utilized in academic and industrial R&D for exploring new reactions of multi-functionalized polycyclic aromatic hydrocarbons.

Basic Information

Product Name	1,3,6-Trisulfonylpyrene 8-Isothiocyanate
CAS No.	58226-67-8
Molecular Formula	C21H9NO9S4
Molecular Weight	571.56 g/mol
Synonyms	Pyrene-1,3,6-trisulfonyl 8-isothiocyanate; 8-Isothiocyanato-1,3,6-pyrenetrisulfonic acid; 1,3,6-Pyrenetrisulfonic acid, 8-isothiocyanato-; Trisulfonated pyrene isothiocyanate; Pyrene trisulfonate isothiocyanate; PTS-ITC; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1,3,6-Trisulfonylpyrene 8-Isothiocyanate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.