Description

(Endo,Anti)-(±)-3-(3-Hydroxy-1-Oxo-2-Phenylpropoxy)-8-Isopropyl-8-Methyl-8-Azoniabicyclo[3.2.1]Octane Bromide is a high-purity, complex organic salt with significant pharmaceutical relevance. This compound is valued for its precise stereochemistry and serves as a critical advanced pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing and scaling up new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those targeting the nervous system.
• Active Pharmaceutical Ingredient (API) Development: Used in research and development for creating new candidate drugs.
• Chemical Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and quality control.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize drug efficacy and safety profiles.
• Process Chemistry & Scale-Up: Utilized in pilot plants and manufacturing for process optimization and validation.
• Contract Manufacturing (CMO/CDMO): Supplied to contract organizations for the production of specialized and generic pharmaceuticals.

Basic Information

Item	Details
Product Name	(Endo,Anti)-(±)-3-(3-Hydroxy-1-Oxo-2-Phenylpropoxy)-8-Isopropyl-8-Methyl-8-Azoniabicyclo[3.2.1]Octane Bromide
CAS No.	58073-59-9
Molecular Formula	C₂₀H₃₀BrNO₄
Molecular Weight	428.36 g/mol
Synonyms	8-Isopropyl-8-methyl-8-azoniabicyclo[3.2.1]octane bromide, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-, (1R,2R,3S,5S)-rel-; Tropine 3-(3-hydroxy-2-phenylpropionate) methobromide; 3α-Hydroxy-8-isopropyl-8-methyl-8-azoniabicyclo[3.2.1]octane bromide, 3-(3-hydroxy-2-phenylpropionate); 8-Methyl-8-isopropylnoratropinium bromide; Atropine N-isopropyl bromide derivative; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our (Endo,Anti)-(±)-3-(3-Hydroxy-1-Oxo-2-Phenylpropoxy)-8-Isopropyl-8-Methyl-8-Azoniabicyclo[3.2.1]Octane Bromide is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant pharmacopeial tests. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Avoid prolonged exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.