Description

5'α-Benzyl-12'-Hydroxy-2'-Isopropylergotaman-3',6',18-Trione Methanesulphonate is a high-purity, complex ergot alkaloid derivative with significant research and pharmaceutical development potential. Its intricate structure makes it a valuable intermediate for synthesizing novel compounds targeting specific neurological and vascular receptors. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in advanced medicinal chemistry and drug discovery programs. Consistent quality and reliable supply are paramount for these critical applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel ergot-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in studies investigating serotonin (5-HT) and dopamine receptor interactions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new therapeutic agents for migraines or neurological disorders.
• Process Development: Acts as a critical intermediate in scaling up and optimizing synthetic routes for complex alkaloid production.
• Analytical Standard: Provides a high-purity compound for method development and validation in quality control laboratories.

Basic Information

Product Name	5'α-Benzyl-12'-Hydroxy-2'-Isopropylergotaman-3',6',18-Trione Methanesulphonate
CAS No.	57884-92-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5'α-Benzyl-12'-hydroxy-2'-isopropylergotaman-3',6',18-trione methanesulfonate; 2'-Isopropyl-5'α-benzyl-12'-hydroxyergotaman-3',6',18-trione methanesulfonate; Ergotaman derivative, 5'α-Benzyl-12'-Hydroxy-2'-Isopropyl-3',6',18-Trione Methanesulphonate; Methanesulfonic acid compound with 5'α-Benzyl-12'-Hydroxy-2'-Isopropylergotaman-3',6',18-Trione
EINECS	Contact for details

Quality Control

Our 5'α-Benzyl-12'-Hydroxy-2'-Isopropylergotaman-3',6',18-Trione Methanesulphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.