Description

2-Chloro-5-Fluorobenzoic Acid Ethyl Ester is a high-purity fluorinated benzoate ester derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it an invaluable intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the chloro-fluoro aromatic moiety is required for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials for electronic displays.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterifications, and as a scaffold for constructing complex polycyclic aromatic compounds in research laboratories.
• Chemical Research & Development: Essential for medicinal chemistry programs and material science research exploring new fluorinated compounds.

Basic Information

Product Name	2-Chloro-5-Fluorobenzoic Acid Ethyl Ester
CAS No.	57381-63-2
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	Ethyl 2-Chloro-5-fluorobenzoate; 2-Chloro-5-fluorobenzoic Acid Ethyl Ester; Benzoic acid, 2-chloro-5-fluoro-, ethyl ester; 5-Fluoro-2-chlorobenzoic Acid Ethyl Ester; Ethyl 5-Fluoro-2-chlorobenzoate; 57381-63-2; 2-Chloro-5-fluorobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Fluorobenzoic Acid Ethyl Ester is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request, supporting compliance in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.