Description

Tolerin CAS NO 57125-68-5 is a high-purity chemical compound, also known as 2,4,6-Triisopropylbenzenesulfonyl chloride, valued for its role as a versatile sulfonating and protecting agent in complex organic syntheses. Its consistent quality and reactivity make it a critical reagent for ensuring high yields and purity in multi-step manufacturing processes. This product is essential for research laboratories and production facilities in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents requiring selective sulfonylation.
• Peptide Chemistry: Serves as a protecting group for amino acids during solid-phase and solution-phase peptide synthesis.
• Material Science: Intermediate in the creation of specialty polymers, dyes, and photoinitiators.
• Organic Synthesis Reagent: Employed as a sulfonyl chloride source for introducing the sulfonyl moiety into various organic molecules in research and development.
• Chemical Research: A valuable tool in academic and industrial R&D for exploring new synthetic pathways and methodologies.

Basic Information

Product Name	Tolerin
CAS No.	57125-68-5
Molecular Formula	C15H23ClO2S
Molecular Weight	302.86 g/mol
Synonyms	2,4,6-Triisopropylbenzenesulfonyl chloride; 2,4,6-Triisopropylphenylsulfonyl chloride; TIPS-Cl; Trisyl chloride; TPS-Cl; Benzenesulfonyl chloride, 2,4,6-triisopropyl-; Tolerin (trade name)
EINECS	Contact for details

Quality Control

Every batch of Tolerin (CAS 57125-68-5) is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.