Description

n-Acetylmuramyl-D-Alanyl-D-Isoglutamine is a key synthetic muramyl dipeptide (MDP) derivative, serving as a fundamental building block in immunology and pharmaceutical research. This compound is valued for its role as the minimal bioactive peptidoglycan fragment capable of stimulating immune responses. It is primarily required by research institutions and pharmaceutical developers focused on vaccine adjuvants, immunostimulants, and the study of innate immune system pathways, including NLR activation.

Application

• Immunological Research: Fundamental studies on NOD2 receptor activation and innate immune signaling pathways.
• Vaccine Adjuvant Development: Investigation and formulation of novel adjuvants to enhance vaccine efficacy.
• Pharmaceutical Intermediates: Synthesis of more complex immunomodulatory compounds and prodrugs.
• Cell Culture & In Vitro Studies: Used to stimulate immune cells in experimental models to study cytokine production and cellular responses.
• Bioconjugation: Serving as a hapten or target moiety in the development of diagnostic tools and targeted therapies.

Basic Information

Product Name	n-Acetylmuramyl-D-Alanyl-D-Isoglutamine
CAS No.	56816-18-3
Molecular Formula	C19H32N4O11
Molecular Weight	492.48 g/mol
Synonyms	Muramyl Dipeptide (MDP); N-Acetylmuramyl-L-alanyl-D-isoglutamine; Ac-MDP; MDP-Lys(L18); Adjuvant Peptide; LK-409; 6-O-2-Acetamido-2-deoxy-3-O-[(R)-1-carboxyethyl]-β-D-glucopyranosyl-(1→4)-N-acetylmuramyl-L-alanyl-D-isoglutamine; N-Acetylmuramyl-L-Ala-D-isoGln
EINECS	Contact for details

Quality Control

Our n-Acetylmuramyl-D-Alanyl-D-Isoglutamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation by IR and NMR spectroscopy. Certificates of Analysis (COA) with detailed specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.