Description

Dabsyl Chloride CAS NO 56512-49-3 is a highly reactive derivatization reagent primarily used for the pre-column labeling of amino acids, peptides, and amines in high-performance liquid chromatography (HPLC). Its core value lies in forming stable, strongly UV-absorbing derivatives that enable highly sensitive detection and quantification at trace levels. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and food science industries, where precise amino acid analysis is critical for product development, purity assessment, and metabolic studies.

Application

• Pre-column derivatization for HPLC analysis of amino acids, peptides, and primary/secondary amines.
• Sensitive detection in protein sequencing and peptide mapping applications.
• Quantification of amino acids in biological fluids, cell culture media, and hydrolysates.
• Food and beverage analysis for determining amino acid profiles and nutritional content.
• Pharmaceutical quality control for testing the purity and composition of peptide-based drugs and APIs.
• Metabolomics and proteomics research to study biochemical pathways and biomarker discovery.
• Derivatization agent in capillary electrophoresis (CE) for enhanced sensitivity.

Basic Information

Product Name	Dabsyl Chloride
CAS No.	56512-49-3
Molecular Formula	C16H18ClN3O2S
Molecular Weight	351.85 g/mol
Synonyms	4-Dimethylaminoazobenzene-4'-sulfonyl Chloride; DABS-CI; Dabsyl Chloride; DABS-Cl; Dabsyl Chloride Reagent; 4-(Dimethylamino)azobenzene-4'-sulfonyl Chloride; DABS Chloride; Dabsyl Chloride, for HPLC derivatization
EINECS	Contact for details

Quality Control

Our Dabsyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for analytical applications. Each lot undergoes rigorous testing, including HPLC assay, identity confirmation (IR), and purity verification. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for research and analytical reagent grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and opened under controlled conditions to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	168 - 172 °C
Loss on Drying	≤ 1.0 %
Related Substances (HPLC)	Total impurities ≤ 2.0%
Suitability for Derivatization	Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.