Description

N,2-Didehydro-1,4-Dideoxy-1,2-Dihydro-4-[(2R)-2-[(S)-1-Hydroxyethyl]-1-Pyrrolidinyl]-1-Oxorifamycin is a key semi-synthetic derivative of the rifamycin class of antibiotics, valued for its potent antibacterial activity. This compound is critical for pharmaceutical research and development, particularly in the fight against drug-resistant bacterial strains. It serves as a vital intermediate and reference standard for manufacturers and research institutions focused on developing next-generation antimicrobial therapies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced rifamycin-based antibiotics.
• Antimicrobial Research: Used as a reference standard and active compound in R&D for novel antibacterial agents targeting resistant infections.
• Biochemical Studies: Employed in studies investigating the mechanism of action of RNA polymerase inhibition in bacteria.
• Analytical Standard: Serves as a high-purity standard for quality control and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical manufacturing.
• Veterinary Medicine Development: Potential use in developing antibacterial treatments for veterinary applications.

Basic Information

Product Name	N,2-Didehydro-1,4-Dideoxy-1,2-Dihydro-4-[(2R)-2-[(S)-1-Hydroxyethyl]-1-Pyrrolidinyl]-1-Oxorifamycin
CAS No.	56413-94-6
Molecular Formula	C39H48N2O12
Molecular Weight	736.81 g/mol
Synonyms	Rifamycin Derivative 56413-94-6; 25-Deacetyl-25-(1-hydroxyethyl)rifamycin S; 25-O-Desacetyl-25-(1-hydroxyethyl)rifamycin S; 3-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin SV; (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-21-Acetoxy-6,9,17,19-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-5-yl acetate; Rifampicin Quinone; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our N,2-Didehydro-1,4-Dideoxy-1,2-Dihydro-4-[(2R)-2-[(S)-1-Hydroxyethyl]-1-Pyrrolidinyl]-1-Oxorifamycin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	Reddish-brown to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.