Description

Piretanide CAS NO 55837-27-9 is a high-purity loop diuretic compound belonging to the sulfonamide class. It is a critical active pharmaceutical ingredient (API) valued for its potent diuretic and antihypertensive properties. This compound is essential for pharmaceutical manufacturers and research institutions developing and producing advanced cardiovascular and renal medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of prescription diuretic medications for treating edema associated with congestive heart failure, renal disease, and hepatic cirrhosis.
• Hypertension Treatment: Key component in antihypertensive drug formulations to manage high blood pressure.
• Biomedical Research: Used as a reference standard and research tool in pharmacological studies investigating renal sodium-potassium-chloride co-transporter (NKCC2) inhibition and electrolyte balance.
• Analytical Standard: Serves as a certified reference material (CRM) for quality control and assay development in analytical laboratories.
• Preclinical & Clinical Development: Employed in the research and development of new therapeutic entities targeting fluid retention and cardiovascular disorders.

Basic Information

Product Name	Piretanide
CAS No.	55837-27-9
Molecular Formula	C₁₇H₁₈N₂O₅S
Molecular Weight	362.40 g/mol
Synonyms	4-Phenoxy-3-(1-pyrrolidinyl)-5-sulfamoylbenzoic Acid; Hoe-118; Arlix; Tauliz; Perbil; Arelix; Piretanidum; 3-(Pyrrolidin-1-yl)-4-phenoxy-5-sulfamoylbenzoic Acid
EINECS	Contact for details

Quality Control

Our Piretanide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmaceutical-grade specifications for identity, purity, and potency. A detailed Certificate of Analysis (COA) confirming compliance with relevant pharmacopeial standards (e.g., USP, EP) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.