Description

Vancomycin Cdp-1 is a key intermediate in the synthesis of the glycopeptide antibiotic vancomycin. This compound is of critical importance for pharmaceutical research and development, enabling the study of vancomycin's structure-activity relationships and the production of novel derivatives. It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in antibiotic development and advanced synthetic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the chemical synthesis and semi-synthesis of vancomycin and its analogs.
• Antibiotic Research: Used in biochemical and microbiological research to investigate mechanisms of action and resistance against Gram-positive bacteria.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical labs.
• Process Development: Employed in the scale-up and optimization of vancomycin production processes within API (Active Pharmaceutical Ingredient) manufacturing.
• Structure-Activity Relationship (SAR) Studies: Essential for medicinal chemistry programs aimed at modifying the vancomycin scaffold to improve efficacy or overcome bacterial resistance.

Basic Information

Product Name	Vancomycin Cdp-1
CAS No.	55598-85-1
Molecular Formula	C66H75Cl2N9O24
Molecular Weight	1449.2 g/mol
Synonyms	CDP-I; Vancomycin CDP-I; Chloroeremomycin CDP-1; (3S,6R,9S,12R,15S,18R,21S,24R,30S,33S)-30-[[2-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)-β-D-glucopyranosyl]oxy]-12-[(2R,3R,4S,5S,6R)-4-(carbamoylmethyl)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-15-[(2R,3R,4S,5S,6R)-4-(2-amino-2-oxoethyl)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-3-[(2R,3S,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-6-[(1R)-1-hydroxyethyl]-18-[(4-hydroxyphenyl)methyl]-21-(1H-indol-3-ylmethyl)-9,24-bis(2-methylpropyl)-2,5,8,11,14,17,20,23,26,29,32-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazatetratriacontane-33-carboxylic acid; A82846B CDP-1
EINECS	Contact for details

Quality Control

Our Vancomycin Cdp-1 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.