Description

Naphthomycin is a complex ansamycin-class antibiotic derived from Streptomyces species. This compound is valued for its potent biological activity, particularly as a lead structure in pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel antibacterial and antitumor agents. Our supply of Naphthomycin CAS NO 55557-40-9 ensures high purity and batch-to-batch consistency critical for sensitive biological assays.

Application

• Pharmaceutical Research: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in antibiotic discovery programs.
• Antimicrobial Studies: Used in microbiological research to study mechanisms of action against Gram-positive bacteria and mycobacteria.
• Oncology Research: Investigated for its cytotoxic properties and potential as a scaffold for developing novel anticancer therapeutics.
• Biochemical Tool: Employed in enzymatic studies, particularly those involving bacterial RNA polymerase inhibition.
• Standards and Controls: Provides a certified standard for quality control and analytical method development in regulatory and compliance testing.

Basic Information

Product Name	Naphthomycin
CAS No.	55557-40-9
Molecular Formula	C₄₃H₅₆N₂O₉
Molecular Weight	744.92 g/mol
Synonyms	Naphthomycin A; Antibiotic SL 2266; Ansamycin antibiotic SL 2266; 5,6,7,8-Tetrahydro-19-demethyl-4,5-dihydro-19-oxonaphthomycin; 19-Demethyl-19-oxonaphthomycin; SL-2266; Antibiotic SL-2266
EINECS	Contact for details

Quality Control

Our Naphthomycin is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and microbial limit tests. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade material specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. Allow the container to reach room temperature in a desiccator before opening to prevent condensation. Store in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 1.0%
Biological Activity	Assay available upon request

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.