Description

Heptanedioic Acid Bis(Trimethylsilyl) Ester is a high-purity silylating reagent and synthetic intermediate, valued for its role in protecting reactive functional groups and facilitating complex organic syntheses. Its primary commercial value lies in enabling precise chemical modifications in sensitive applications where moisture control is critical. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Derivatization Agent in Analytical Chemistry: Used to enhance the volatility and thermal stability of polar compounds (e.g., carboxylic acids, alcohols) for Gas Chromatography (GC) and GC-MS analysis.
• Key Synthetic Intermediate: Serves as a protected form of pimelic acid (heptanedioic acid) in multi-step organic synthesis, particularly in the production of pharmaceuticals and fine chemicals.
• Silicon-Based Reagent: Employed in silylation reactions to introduce trimethylsilyl (TMS) groups, protecting sensitive moieties from unwanted side reactions during synthesis.
• Polymer and Material Science: Acts as a monomer or modifying agent in the synthesis of specialized silicon-containing polymers and hybrid materials.
• Cross-Coupling Reactions: Can be utilized as a substrate in palladium-catalyzed cross-coupling reactions to construct complex molecular architectures.
• Laboratory Reagent: Used in research settings for method development and the synthesis of novel chemical entities.

Basic Information

Product Name	Heptanedioic Acid Bis(Trimethylsilyl) Ester
CAS No.	55530-58-0
Molecular Formula	C13H30O4Si2
Molecular Weight	306.55 g/mol
Synonyms	Pimelic Acid Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) Pimelate; Bis(trimethylsilyl) Heptanedioate; Heptanedioic Acid, Bis(trimethylsilyl) Ester; 1,7-Bis(trimethylsilyloxy)-1,7-dioxoheptane; TMS Pimelate; Pimelic Acid TMS Ester; Trimethylsilyl Pimelate
EINECS	Contact for details

Quality Control

Our Heptanedioic Acid Bis(Trimethylsilyl) Ester is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product integrity. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.