Description

5-(3,4-Difluorophenyl)-Furan-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a furan carboxylic acid moiety with a difluorinated phenyl ring, making it a versatile intermediate for creating complex molecules with tailored properties. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a crucial building block for creating new-generation herbicides, fungicides, and insecticides, where the difluorophenyl group can enhance bioavailability and environmental stability.
• Material Science Research: Used in the synthesis of specialized monomers for advanced polymers, liquid crystals, or organic electronic materials, leveraging its rigid, aromatic structure.
• Chemical Biology & Probe Development: Employed as a scaffold for designing fluorescent probes, enzyme inhibitors, or other molecular tools for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	5-(3,4-Difluorophenyl)-Furan-2-Carboxylic Acid
CAS No.	55377-81-6
Molecular Formula	C11H6F2O3
Molecular Weight	224.16 g/mol
Synonyms	5-(3,4-Difluorophenyl)-2-furancarboxylic acid; 2-Furoic acid, 5-(3,4-difluorophenyl)-; 3,4-Difluorophenylfuran-2-carboxylic Acid; 5-(3,4-Difluorophenyl)furan-2-carboxylic acid; 2-Furancarboxylic acid, 5-(3,4-difluorophenyl)-; 55377-81-6; 5-(3,4-Difluorophenyl)-2-furoic acid
EINECS	Contact for details

Quality Control

Our 5-(3,4-Difluorophenyl)-Furan-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases and incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.