Description

4-o-[2-(3,5-Dimethyl-4-Morpholinyl)-2-Oxoethyl]Rifamycin is a semi-synthetic derivative of the rifamycin class of antibiotics, characterized by its specific chemical modification at the 4-position. This compound is valued for its role as a key intermediate in the research and development of novel antimicrobial agents, particularly against resistant bacterial strains. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focused on anti-infective therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced rifamycin analogs and next-generation antibiotics.
• Antimicrobial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) and mechanisms of action against bacteria.
• API Development: Employed in the process development and scale-up manufacturing of novel antibacterial active pharmaceutical ingredients.
• Reference Standard: Functions as a high-purity chemical reference standard for analytical method development and quality control in pharmaceutical analysis.
• Preclinical Studies: Utilized in in-vitro and in-vivo studies to evaluate the efficacy, pharmacokinetics, and toxicity of new anti-infective drug candidates.

Basic Information

Product Name	4-o-[2-(3,5-Dimethyl-4-Morpholinyl)-2-Oxoethyl]Rifamycin
CAS No.	55372-15-1
Molecular Formula	C41H52N2O13
Molecular Weight	780.86 g/mol
Synonyms	4-Deoxy-3,4-[2-(3,5-dimethyl-4-morpholinyl)-2-oxoethylidene]rifamycin S; Rifamycin Derivative 55372-15-1; 4-O-(2-(3,5-Dimethyl-4-morpholinyl)-2-oxoethyl)rifamycin; 4-Deoxy-3,4-[2-(3,5-dimethylmorpholino)-2-oxoethylidene]rifamycin S
EINECS	Contact for details

Quality Control

Our 4-o-[2-(3,5-Dimethyl-4-Morpholinyl)-2-Oxoethyl]Rifamycin is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents. We can supply material suitable for research and development purposes, with the capability to meet specific purity requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain stability.

Specification

Item	Specification
Appearance	Reddish-brown to orange powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.