Description

Nalmefene CAS NO 55096-26-9 is a potent opioid receptor antagonist, structurally related to naltrexone. This compound is critical for pharmaceutical research and development, particularly in the fields of addiction medicine and neurology. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in the development of treatments for alcohol and opioid dependence.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of medications targeting alcohol use disorder.
• Reference Standard in analytical chemistry for quality control and method validation in pharmaceutical labs.
• Biochemical Research tool for studying opioid receptor mechanisms, binding affinity, and signal transduction pathways.
• Preclinical Development for pharmacokinetic (PK) and pharmacodynamic (PD) studies in animal models.
• Process Chemistry as a key intermediate or final product in the synthesis of related opioid antagonists.

Basic Information

Product Name	Nalmefene
CAS No.	55096-26-9
Molecular Formula	C21H25NO3
Molecular Weight	339.43 g/mol
Synonyms	Nalmefene; 17-(Cyclopropylmethyl)-4,5α-epoxy-6-methylenemorphinan-3,14-diol; (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol; Nalmetrene; ORF 11676; Revex
EINECS	Contact for details

Quality Control

Our Nalmefene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing results from HPLC, NMR, and other relevant pharmacopeial tests.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.