Description

Ribo-Oligonucleotide A(7)U(7) CAS NO 54651-08-0 is a defined-sequence, single-stranded RNA oligonucleotide composed of seven adenine (A) and seven uracil (U) ribonucleotides. This compound is a critical research-grade biochemical tool for studying RNA structure, function, and interactions. It is primarily utilized by academic, biotechnology, and pharmaceutical research institutions engaged in molecular biology, nucleic acid chemistry, and therapeutic development. The defined sequence provides a consistent and reliable substrate for a wide range of experimental applications.

Application

• Biochemical Research: Used as a model substrate for studying RNA-RNA and RNA-protein interactions, hybridization kinetics, and duplex stability.
• Enzyme Assay Development: Serves as a standard or control in assays for ribonucleases (RNases), helicases, polymerases, and other RNA-modifying enzymes.
• Therapeutic Discovery: Acts as a precursor or model compound in the research and development of antisense oligonucleotides, siRNA, and other RNA-based therapeutics.
• Diagnostic Probe Development: Can be used in the design and validation of hybridization probes for diagnostic assays and biosensors.
• Structural Biology: Provides a homogeneous sample for techniques like NMR spectroscopy and X-ray crystallography to determine RNA secondary and tertiary structures.
• Quality Control Standard: Employed as a reference material in the quality control of oligonucleotide synthesis and purification processes.

Basic Information

Product Name	Ribo-Oligonucleotide A(7)U(7)
CAS No.	54651-08-0
Molecular Formula	C140H175N49O91P14
Molecular Weight	Contact for details
Synonyms	RNA Oligonucleotide A7U7; Polyadenylic-polyuridylic acid heptamer; r(A)7r(U)7; Adenine-Uracil RNA heptadecamer; 7A-7U Ribooligonucleotide; Oligoribonucleotide (A7U7); rA7rU7; AU Repeating Sequence RNA
EINECS	Contact for details

Quality Control

Our Ribo-Oligonucleotide A(7)U(7) is produced under stringent conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment, mass spectrometry (MS) for identity confirmation, and UV spectroscopy for quantification. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Sequence Verification (MS)	Conforms to A(7)U(7)
UV Absorbance Ratio (A260/A280)	2.0 - 2.2
Water Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.