Description

Benzoic Acid, 2-(Phenylmethoxy)-5-(Trifluoromethyl)- is a specialized aromatic carboxylic acid derivative, distinguished by the presence of a benzyloxy group and a trifluoromethyl substituent. This unique molecular structure imparts valuable properties, making it a critical advanced pharmaceutical intermediate and a versatile building block in fine chemical synthesis. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional compounds. The CAS number for this compound is 53985-54-9.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides and fungicides, leveraging the stability of the trifluoromethyl group.
• Liquid Crystal & OLED Material Research: Used in the development of novel organic electronic materials due to its aromatic core and functional group versatility.
• Polymer Modification: Acts as a monomer or additive to introduce specific functional groups into polymer chains, enhancing material properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a protecting group precursor in complex multi-step synthetic routes.
• Dye & Pigment Intermediate: Utilized in the production of specialized colorants and photographic chemicals.

Basic Information

Product Name	Benzoic Acid, 2-(Phenylmethoxy)-5-(Trifluoromethyl)-
CAS No.	53985-54-9
Molecular Formula	C15H11F3O3
Molecular Weight	296.24 g/mol
Synonyms	2-(Benzyloxy)-5-(trifluoromethyl)benzoic Acid; 5-(Trifluoromethyl)-2-(phenylmethoxy)benzoic Acid; α,α,α-Trifluoro-2-(benzyloxy)-5-methylbenzoic Acid; 2-Benzyloxy-5-trifluoromethylbenzoic Acid; o-Benzyloxy-α,α,α-trifluoro-m-toluic Acid; BTFBA (common abbreviation); [2-(Phenylmethoxy)-5-(trifluoromethyl)phenyl]formic Acid
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 2-(Phenylmethoxy)-5-(Trifluoromethyl)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the exacting standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support audits and regulatory documentation as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.