Description

5-Methoxymethyl-2'-Deoxyuridine-5'-Monophosphate is a modified nucleoside monophosphate, a key building block in the synthesis of oligonucleotides and nucleotide analogs. This compound is critical for research and development in advanced therapeutic areas, including antiviral and anticancer drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on nucleic acid chemistry and medicinal chemistry.

Application

• Oligonucleotide Synthesis: Serves as a modified phosphoramidite precursor for the solid-phase synthesis of therapeutic and diagnostic oligonucleotides.
• Antiviral Drug Development: Used as an intermediate in the research and production of nucleoside analog prodrugs targeting viral polymerases.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleotide-based therapeutics.
• Biochemical Probes: Employed in the development of labeled nucleotides for studying enzyme mechanisms, such as those of DNA polymerases and kinases.
• Precision Medicine: Potential use in the synthesis of personalized therapeutic agents, including antisense oligonucleotides and siRNA.

Basic Information

Product Name	5-Methoxymethyl-2'-Deoxyuridine-5'-Monophosphate
CAS No.	53212-98-9
Molecular Formula	C12H17N2O9P
Molecular Weight	364.25 g/mol
Synonyms	5-Methoxymethyl-dUMP; 5-Methoxymethyl-2'-deoxyuridine 5'-(dihydrogen phosphate); 5-(Methoxymethyl)-2'-deoxyuridine 5'-monophosphate; 5-MM-dUMP; 2'-Deoxy-5-methoxymethyluridine 5'-monophosphate; 5-Methoxymethyl-2'-deoxyuridylic acid; dUMP(5-MM)
EINECS	Contact for details

Quality Control

Our 5-Methoxymethyl-2'-Deoxyuridine-5'-Monophosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.