Description

2,4-Bis(Trifluoromethyl)Benzoyl Chloride is a high-value, reactive aromatic acid chloride derivative, distinguished by its two electron-withdrawing trifluoromethyl groups. This structural motif is critical for its role as a versatile and potent building block in advanced organic synthesis, enabling the introduction of the 2,4-bis(trifluoromethyl)benzoyl moiety. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced properties such as metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer & Resin Modification: Employed to introduce fluorinated aromatic units into polymer chains, enhancing material properties like chemical resistance, thermal stability, and low surface energy.
• Advanced Material Research: A crucial reagent in academic and industrial R&D for creating novel fluorinated compounds with specialized optical, electronic, or surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules and complex intermediates.

Basic Information

Product Name	2,4-Bis(Trifluoromethyl)Benzoyl Chloride
CAS No.	53130-43-1
Molecular Formula	C9H3ClF6O
Molecular Weight	276.56 g/mol
Synonyms	2,4-Bis(trifluoromethyl)benzoyl chloride; α,α,α,α',α',α'-Hexafluoro-2,4-xylene-α-carbonyl chloride; 2,4-Bis(trifluoromethyl)benzoic acid chloride; 2,4-Di(trifluoromethyl)benzoyl chloride; Benzoyl chloride, 2,4-bis(trifluoromethyl)-; 2,4-BTFMBC; 2,4-Bis(trifluoromethyl)benzoylchloride
EINECS	Contact for details

Quality Control

Our 2,4-Bis(Trifluoromethyl)Benzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to support cGMP and ISO standards for traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.