Description

Methyl 3-Bromo-2,4,5,6-Tetrafluorobenzoate is a high-purity fluorinated aromatic building block, specifically a multi-halogenated benzoate ester. This compound is valued for its unique reactivity profile, serving as a critical intermediate in the synthesis of complex molecules where precise fluorine and bromine substitution patterns are required. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies, improving performance and durability.
• Polymer Modification: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced chemical resistance and thermal properties.
• Organic Synthesis & Catalysis Research: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and as a substrate for studying new fluorination methodologies.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Methyl 3-Bromo-2,4,5,6-Tetrafluorobenzoate
CAS No.	53001-69-7
Molecular Formula	C8H3BrF4O2
Molecular Weight	287.01 g/mol
Synonyms	3-Bromo-2,4,5,6-tetrafluorobenzoic acid methyl ester; Methyl 3-bromotetrafluorobenzoate; Benzoic acid, 3-bromo-2,4,5,6-tetrafluoro-, methyl ester; Methyl ester of 3-bromo-2,4,5,6-tetrafluorobenzoic acid; 2,4,5,6-Tetrafluoro-3-bromobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Bromo-2,4,5,6-Tetrafluorobenzoate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for cGMP and ISO-guided manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.