Description

2'-Deoxyguanosine-5'-Monophosphate Disodium Salt is a high-purity nucleotide building block essential for life science research and pharmaceutical development. This compound serves as a critical raw material for the synthesis of oligonucleotides, DNA probes, and primers used in molecular biology and diagnostics. It is primarily utilized by manufacturers in the biotechnology, pharmaceutical, and diagnostic industries for applications ranging from PCR to therapeutic nucleic acid synthesis.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for solid-phase synthesis of DNA and RNA sequences.
• PCR & Molecular Diagnostics: Used in the formulation of nucleotide mixes for polymerase chain reaction (PCR) and next-generation sequencing (NGS).
• Therapeutic Nucleic Acids: A vital component in the manufacture of antisense oligonucleotides, siRNA, and aptamers for therapeutic applications.
• Biochemical Research: Employed as a substrate for enzymatic studies involving polymerases, kinases, and other nucleotide-metabolizing enzymes.
• Diagnostic Kits: Incorporated into diagnostic assays and kits for genetic testing and pathogen detection.
• Cell Culture Media: Used as a supplement in specialized cell culture media formulations.

Basic Information

Product Name	2'-Deoxyguanosine-5'-Monophosphate Disodium Salt
CAS No.	52558-16-4
Molecular Formula	C10H12N5Na2O7P
Molecular Weight	391.18 g/mol
Synonyms	dGMP Disodium Salt; 2'-Deoxy-GMP Disodium Salt; Deoxyguanylic Acid Disodium Salt; Sodium 2'-Deoxyguanylate; 5'-dGMP Na2; dG-5'-Monophosphate Disodium Salt; Guanosine-5'-monophosphate, 2'-deoxy-, disodium salt
EINECS	Contact for details

Quality Control

Our 2'-Deoxyguanosine-5'-Monophosphate Disodium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive life science applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 standards, and our quality protocols are designed to meet the rigorous demands of pharmaceutical and diagnostic manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.5 - 8.5
Related Substances (HPLC)	Total impurities ≤ 2.0%
Endotoxin (LAL)	< 10 EU/mg (if required)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.