Description

3-[[[[(E)-3,7-Dimethyl-2,6-Octadienyl]Oxy]Imino]Methyl]Rifamycin Sv is a semi-synthetic derivative of the potent ansamycin antibiotic, rifamycin SV, designed to enhance its pharmacological profile. This compound is of significant interest for its potential to improve antimicrobial efficacy and pharmacokinetic properties compared to its parent molecule. It is primarily utilized by pharmaceutical R&D teams and manufacturers engaged in developing advanced antibiotic formulations and novel therapeutic agents targeting resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of next-generation rifamycin-class antibiotics for clinical development.
• Antimicrobial Research: Used in microbiological and biochemical research to study structure-activity relationships (SAR) and mechanisms of action against Gram-positive bacteria and Mycobacterium tuberculosis.
• API Development: Investigated as a potential active pharmaceutical ingredient (API) in formulations aimed at overcoming bacterial resistance.
• Veterinary Medicine: Exploration of applications in veterinary pharmaceuticals for treating bacterial infections in animals.

Basic Information

Product Name	3-[[[[(E)-3,7-Dimethyl-2,6-Octadienyl]Oxy]Imino]Methyl]Rifamycin Sv
CAS No.	52437-59-9
Molecular Formula	C43H57N3O12
Molecular Weight	807.93 g/mol
Synonyms	Rifamycin SV, 3-[(E)-[[(2E,6E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy]imino]methyl] derivative; 3-Formylrifamycin SV O-(3,7-Dimethyl-2,6-octadienyl)oxime; (E)-3-[[(3,7-Dimethyl-2,6-octadienyloxy)imino]methyl]rifamycin SV; Rifamycin SV geranyloxime derivative; Antibiotic X 5108 (derivative); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-[[[[(E)-3,7-Dimethyl-2,6-Octadienyl]Oxy]Imino]Methyl]Rifamycin Sv is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development purposes. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Reddish-brown to orange powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.