Description

3-[(6-Hydroxyhexyl)Oxyiminomethyl]Rifamycin Sv is a chemically modified derivative of the potent ansamycin antibiotic rifamycin SV, designed to enhance its pharmacokinetic properties and therapeutic potential. This semi-synthetic compound is critical for pharmaceutical research and development, particularly in the creation of advanced antibacterial agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing novel treatments for bacterial infections, especially those caused by Gram-positive organisms and Mycobacterium tuberculosis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of next-generation rifamycin antibiotics with improved bioavailability and efficacy.
• Antibacterial Research: Used in microbiological and pharmacological studies to investigate new mechanisms of action against drug-resistant bacterial strains.
• Prodrug Development: Serves as a precursor in the design of prodrug formulations aimed at enhancing solubility and targeted delivery.
• Biochemical Tool: Employed in laboratory settings to study bacterial RNA polymerase inhibition and related biochemical pathways.
• API Synthesis: Integral in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) for anti-tuberculosis and anti-staphylococcal medications.

Basic Information

Product Name	3-[(6-Hydroxyhexyl)Oxyiminomethyl]Rifamycin Sv
CAS No.	52370-33-9
Molecular Formula	C₄₃H₅₈N₂O₁₃
Molecular Weight	838.93 g/mol
Synonyms	Rifamycin SV, 3-[(6-Hydroxyhexyl)oxyimino]methyl derivative; 3-Formylrifamycin SV O-(6-hydroxyhexyl)oxime; Rifamycin SV oxime derivative; 3-[(6-Hydroxyhexyl)Oxyiminomethyl]Rifamycin; Antibiotic AF/ABD; (6-Hydroxyhexyl)oximinomethylrifamycin SV
EINECS	Contact for details

Quality Control

Our 3-[(6-Hydroxyhexyl)Oxyiminomethyl]Rifamycin Sv is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon to maintain stability and potency.

Specification

Item	Specification
Appearance	Orange-red to reddish-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.