Description

3-[2-(2-Methoxyethoxy)Ethoxyiminomethyl]Rifamycin Sv is a chemically modified derivative of the potent ansamycin antibiotic, rifamycin SV. This semi-synthetic compound is engineered to enhance solubility and bioavailability, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on developing novel antibacterial agents and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of next-generation rifamycin-based antibiotics.
• Antibacterial Research: Used in R&D for studying structure-activity relationships (SAR) and developing new antimicrobial compounds with improved efficacy.
• Prodrug Development: Serves as a precursor for creating prodrugs designed to enhance patient compliance through better solubility and absorption profiles.
• Biochemical Studies: Employed in laboratory studies to investigate bacterial RNA polymerase inhibition mechanisms.
• Formulation Development: Used in the development of novel injectable or oral dosage forms requiring modified drug solubility.

Basic Information

Product Name	3-[2-(2-Methoxyethoxy)Ethoxyiminomethyl]Rifamycin Sv
CAS No.	52370-30-6
Molecular Formula	C₄₃H₅₈N₂O₁₄
Molecular Weight	838.93 g/mol
Synonyms	Rifamycin SV 3-[2-(2-Methoxyethoxy)ethoxyiminomethyl] Derivative; 3-Formylrifamycin SV O-(2-(2-Methoxyethoxy)ethyl)oxime; Rifamycin SV Derivative 52370-30-6; 3-[(2-(2-Methoxyethoxy)ethoxy)iminomethyl]rifamycin SV; Rifamycin SV Oxime PEG Methyl Ether Derivative
EINECS	Contact for details

Quality Control

Our 3-[2-(2-Methoxyethoxy)Ethoxyiminomethyl]Rifamycin Sv is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Reddish-brown to orange amorphous powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.