Description

5-Dimethylaminonaphthalene-1-Sulfonyl Aziridine is a specialized chemical building block and derivatization reagent, primarily valued for its role in synthesizing advanced fluorescent probes and other functional molecules. Its core value lies in the unique reactivity of the aziridine ring and the fluorescence properties of the dansyl (5-dimethylaminonaphthalene-1-sulfonyl) moiety. This compound is essential for researchers and manufacturers in the life sciences and advanced materials sectors who require high-purity intermediates for labeling, sensing, and polymer modification applications.

Application

• Fluorescent Probe Synthesis: Acts as a key precursor for creating dansyl-labeled fluorescent tags and sensors used in bioimaging and biochemical assays.
• Protein & Peptide Labeling: Utilized as a derivatization reagent to introduce fluorescent labels onto biomolecules for detection and analysis.
• Polymer Functionalization: Serves as a monomer or cross-linking agent for introducing reactive aziridine groups into polymer chains, modifying material properties.
• Pharmaceutical Intermediate: Employed in the research and development of novel drug candidates, particularly those requiring fluorescent markers or specific ring-opening reactions.
• Chemical Biology Research: Used in studying enzyme mechanisms and protein interactions through site-specific labeling strategies.
• Material Science: Applied in the development of smart materials and surfaces with tailored optical or chemical responsiveness.

Basic Information

Product Name	5-Dimethylaminonaphthalene-1-Sulfonyl Aziridine
CAS No.	51908-46-4
Molecular Formula	C₁₄H₁₆N₂O₂S
Molecular Weight	276.35 g/mol
Synonyms	Dansyl Aziridine; 1-Dimethylaminonaphthalene-5-sulfonyl Aziridine; N-(1-Aziridinyl)-5-dimethylaminonaphthalene-1-sulfonamide; DNS-Aziridine; Dns-aziridine; 5-(Dimethylamino)naphthalene-1-sulfonyl Aziridine; Aziridine, 1-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-
EINECS	Contact for details

Quality Control

Our 5-Dimethylaminonaphthalene-1-Sulfonyl Aziridine is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (HPLC), identity (IR, NMR), and impurity profiles. Our quality management system supports compliance with relevant industry standards for fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate to maximize shelf life.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.