Description

3-Chloroformyl-7-Methoxycoumarin is a key reactive intermediate in organic synthesis, prized for its versatile chloroformyl functional group. This compound is essential for researchers and manufacturers requiring a reliable building block to introduce the coumarin fluorophore into more complex molecular architectures. It is primarily utilized in the development of fluorescent probes, sensors, and advanced materials within the pharmaceutical, analytical chemistry, and life science research sectors.

Application

• Fluorescent Probe Synthesis: Acts as a critical precursor for creating highly sensitive fluorescent labels and tags used in bioimaging and diagnostic assays.
• Bioconjugation Reagent: Used to covalently attach fluorophores to proteins, antibodies, peptides, and other biomolecules for detection and analysis.
• Chemical Sensor Development: Serves as a building block in the manufacture of chemosensors for detecting metal ions, anions, or small molecules.
• Pharmaceutical Research: Employed in medicinal chemistry for the synthesis of drug candidates and pharmacologically active compounds containing the coumarin scaffold.
• Material Science: Used in the preparation of advanced organic materials, including light-emitting compounds and polymers with specific optical properties.
• Analytical Chemistry: Functions as a derivatization agent to enhance the detectability of compounds in chromatographic techniques like HPLC.

Basic Information

Product Name	3-Chloroformyl-7-Methoxycoumarin
CAS No.	51867-62-0
Molecular Formula	C11H7ClO4
Molecular Weight	238.62 g/mol
Synonyms	7-Methoxycoumarin-3-carbonyl chloride; 7-Methoxy-3-coumarincarboxylic acid chloride; 3-Carboxy-7-methoxycoumarin chloride; 7-Methoxy-3-chlorocarbonylcoumarin; 3-Chlorocarbonyl-7-methoxy-2H-chromen-2-one; 7-Methoxy-2-oxo-2H-chromene-3-carbonyl chloride; CMMC (Coumarin Methoxy Carbonyl Chloride)
EINECS	Contact for details

Quality Control

Our 3-Chloroformyl-7-Methoxycoumarin is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and synthesis applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of advanced chemical synthesis and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.