Description

3-Heptafluorobutyryl-(+)-Camphor is a high-purity, chiral fluorinated derivative of camphor, serving as a critical chiral derivatizing agent and analytical standard. Its primary value lies in its ability to resolve enantiomers of chiral compounds, particularly amines and alcohols, for precise analysis via techniques like gas chromatography (GC) and nuclear magnetic resonance (NMR). This compound is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and fine chemical industries where stereochemical purity is paramount.

Application

• Chiral Derivatizing Agent (CDA): For the resolution and analysis of enantiomeric mixtures of amines, amino acids, and alcohols via GC, HPLC, or NMR.
• Pharmaceutical Intermediate: Used in the research and development of enantiomerically pure active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Serves as a high-purity standard for method development and validation in chiral separation protocols.
• Asymmetric Synthesis: Acts as a chiral auxiliary or ligand in catalytic asymmetric reactions.
• Agrochemical Research: Employed in the analysis and synthesis of chiral pesticides and herbicides.
• Forensic & Clinical Analysis: Used in the determination of enantiomeric composition in complex biological matrices.

Basic Information

Product Name	3-Heptafluorobutyryl-(+)-Camphor
CAS No.	51800-99-8
Molecular Formula	C₁₅H₁₅F₇O₂
Molecular Weight	360.27 g/mol
Synonyms	(1R,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one 3-heptafluorobutyrate; (+)-3-(Heptafluorobutyryl)camphor; 3-(Perfluorobutyryl)-(+)-camphor; 3-HFB-(+)-Camphor; (1R)-(-)-Camphor 3-(heptafluorobutyryl); FASCAT 3-HFB Camphor; Chiral Derivatization Reagent HFB-Camphor
EINECS	Contact for details

Quality Control

Our 3-Heptafluorobutyryl-(+)-Camphor is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling by HPLC and GC, to ensure it meets the exacting standards required for analytical and synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant after opening to maintain purity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (GC/HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.