Description

1,2-Di13-cis-Docosenoyl-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a phosphatidylcholine with defined 13-cis-docosenoyl (erucoyl) fatty acid chains. This compound is critical for creating stable, well-defined lipid bilayers and vesicles, offering superior consistency for advanced research and development. It is an essential material for scientists and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise control over liposomal and membrane properties.

Application

• Liposome & Nanoparticle Formulation: A key structural component for creating drug delivery vehicles, including long-circulating (stealth) liposomes and lipid nanoparticles (LNPs) for mRNA and gene therapies.
• Membrane Biophysics Research: Used as a standard or model membrane lipid to study membrane fluidity, phase behavior, and protein-lipid interactions due to its specific cis-unsaturated fatty acid profile.
• Biomimetic Coatings & Sensors: Employed in the fabrication of supported lipid bilayers (SLBs) for biosensor development, diagnostic platforms, and surface modification to enhance biocompatibility.
• Cell Culture & Transfection Reagents: A component in specialized cell culture media supplements and as a raw material in the synthesis of cationic lipids for non-viral transfection reagents.
• Cosmetic & Dermal Delivery Systems: Incorporated into high-end cosmetic formulations and topical products as an emulsifier and penetration enhancer for active ingredient delivery.
• Reference Standard & Analytical Testing: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical and lipidomics laboratories.

Basic Information

Product Name	1,2-Di13-cis-Docosenoyl-Sn-Glycero-3-Phosphocholine
CAS No.	51779-95-4
Molecular Formula	C52H100NO8P
Molecular Weight	898.31 g/mol
Synonyms	1,2-Dierucoyl-sn-glycero-3-phosphocholine; Erucoyl Phosphatidylcholine; PC(22:1/22:1); Dierucoylphosphatidylcholine; 1,2-Di(cis-13-docosenoyl)-sn-glycero-3-phosphocholine; (2R)-2,3-Bis[[(13Z)-docos-13-enoyl]oxy]propyl 2-(trimethylazaniumyl)ethyl phosphate; DEPC; DErPC
EINECS	Contact for details

Quality Control

Our 1,2-Di13-cis-Docosenoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and isomer confirmation, NMR for structural verification, and mass spectrometry. We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Under these conditions, the product is typically stable for at least two years. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Isomer Profile (13-cis)	≥ 95% of total fatty acid chains
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%
Peroxide Value	≤ 3.0 meq/kg
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.