Description

3-Amino -Rifamycin S is a key semi-synthetic derivative of the rifamycin antibiotic family, serving as a crucial intermediate in the synthesis of advanced antimicrobial agents. Its primary value lies in enabling the development of potent rifamycin analogs with enhanced pharmacological properties and targeted activity. This compound is essential for pharmaceutical R&D and manufacturing sectors focused on creating next-generation antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of advanced rifamycin antibiotics, such as rifampicin and rifabutin.
• Antimicrobial Research: Used in biochemical and microbiological research to study structure-activity relationships (SAR) and develop novel antibacterial agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of complex antibiotic APIs under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.

Basic Information

Product Name	3-Amino -Rifamycin S
CAS No.	51756-80-0
Molecular Formula	C37H47N3O12
Molecular Weight	725.79 g/mol
Synonyms	3-Aminorifamycin S; 3-Amino-Rifamycin S; 3-Amino-Rifamycin; 3-Aminorifamycin; Rifamycin S, 3-amino-; 3-Amino-25-desacetylrifamycin S; 3-Amino-27-demethoxy-27-oxorifamycin S; 3-Amino-27-O-desmethyl-27-oxorifamycin S
EINECS	Contact for details

Quality Control

Our 3-Amino -Rifamycin S is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with ICH guidelines and relevant pharmacopeial standards to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Reddish-brown to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.