Description

3-[[2-(1-Naphtylacetyl)Hydrazono]Methyl]Rifamycin is a semi-synthetic derivative of the rifamycin class of antibiotics, designed to enhance specific pharmacological properties. This compound is of significant interest for its potential in advanced pharmaceutical research and development, particularly in addressing complex bacterial challenges. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel antimicrobial agents and prodrugs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel rifamycin-based antibiotics and prodrugs.
• Antimicrobial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) against resistant bacterial strains.
• Mechanistic Studies: Employed in research to understand the inhibition mechanisms of bacterial RNA polymerase.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Preclinical Development: Utilized in the early-stage development of new therapeutic candidates targeting gram-positive and mycobacterial infections.

Basic Information

Product Name	3-[[2-(1-Naphtylacetyl)Hydrazono]Methyl]Rifamycin
CAS No.	51707-04-1
Molecular Formula	C41H47N3O12
Molecular Weight	773.83 g/mol
Synonyms	3-[[2-(1-Naphthylacetyl)hydrazinylidene]methyl]rifamycin; Rifamycin Derivative 51707-04-1; 3-Formylrifamycin N'-(1-naphthylacetyl)hydrazone; (E)-3-((2-(Naphthalen-1-yl)acetyl)hydrazono)methyl)rifamycin; 1-Naphthaleneacetic acid, 2-[(E)-(3-formyl-4-methyl-1-oxo-1,4-dihydro-2H-naphtho[2,1-b]pyran-11-yl)methylene]hydrazide
EINECS	Contact for details

Quality Control

Our 3-[[2-(1-Naphtylacetyl)Hydrazono]Methyl]Rifamycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.