Description

4-Fluoro-3-Hydroxybenzoic Acid is a versatile fluorinated aromatic building block with a carboxylic acid and a phenolic hydroxyl group. This bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and manufacturing. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel drug candidates, particularly in fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers used in electronic display technologies.
• Polymer Modification: Incorporated as a monomer or additive to impart specific properties like chemical resistance or thermal stability to polymers.
• Complex Ligand Synthesis: Utilized in organic and coordination chemistry to create specialized chelating agents and catalysts.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorinated compounds and reaction pathways.

Basic Information

Product Name	4-Fluoro-3-Hydroxybenzoic Acid
CAS No.	51446-31-2
Molecular Formula	C7H5FO3
Molecular Weight	156.11 g/mol
Synonyms	3-Hydroxy-4-fluorobenzoic Acid; 4-Fluoro-3-hydroxybenzoic acid; Benzoic acid, 4-fluoro-3-hydroxy-; 4-Fluoro-3-hydroxy-benzoic acid; 4-Fluoro-3-hydroxybenzoic acid (CAS 51446-31-2); 3-Hydroxy-4-fluorobenzoic acid (CAS 51446-31-2); 4-Fluoro-3-hydroxybenzoic acid, 98+%; 4-Fluoro-3-hydroxybenzoic acid, 98%
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Hydroxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	210°C - 215°C
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.