Description

2-Fluoro-5-Hydroxybenzoic Acid is a versatile fluorinated aromatic building block that combines a carboxylic acid group with a phenolic hydroxyl group on a fluorobenzene scaffold. This unique trifunctional structure makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and high-value specialty chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated monomers used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated into polymer chains to impart specific properties like altered solubility, thermal stability, or chemical resistance.
• Complex Ligand Synthesis: Utilized in coordination chemistry to create specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized fluorinated dyes and colorants.

Basic Information

Product Name	2-Fluoro-5-Hydroxybenzoic Acid
CAS No.	51446-30-1
Molecular Formula	C7H5FO3
Molecular Weight	156.11 g/mol
Synonyms	5-Hydroxy-2-fluorobenzoic Acid; 2-Fluoro-5-hydroxybenzoic acid; 2-Fluorogentisic Acid; 2-Fluoro-5-hydroxy-benzoic acid; 2-Fluoro-5-hydroxybenzoic acid (2F5HBA); 2-Fluoro-5-hydroxybenzoic acid, 2F5HBA; 2-Fluoro-5-hydroxybenzoic acid, 2-F-5-HBA; 2-Fluoro-5-hydroxybenzoic acid, 2F-5-HBA
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Hydroxybenzoic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.