Description

Ampicillin-Dicloxacillin Mixture is a synergistic combination of two β-lactam antibiotics, designed to broaden the antibacterial spectrum and combat β-lactamase-producing organisms. This mixture is critical for pharmaceutical manufacturers developing combination antibiotic therapies that offer enhanced efficacy against a wider range of bacterial infections. It is primarily required by the pharmaceutical industry for the formulation of injectable and oral dosage forms, as well as by research institutions for microbiological studies.

Application

• Active Pharmaceutical Ingredient (API) in combination antibiotic formulations.
• Manufacturing of sterile injectable powders for hospital use.
• Production of oral capsules and tablets for broad-spectrum antibacterial therapy.
• Research and development of new antibacterial agents and combination therapies.
• Reference standard in quality control laboratories for analytical testing.
• Component in veterinary pharmaceutical products for treating bacterial infections.

Basic Information

Product Name	Ampicillin-Dicloxacillin Mixture
CAS No.	51004-51-4
Molecular Formula	C16H19N3O4S • C19H17Cl2N3O5S
Molecular Weight	349.41 (Ampicillin) • 470.33 (Dicloxacillin)
Synonyms	Ampicillin and Dicloxacillin Combination; Ampicillin/Dicloxacillin; Ampicillin Dicloxacillin Mixture; Ampicillin-Dicloxacillin; (2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid mixture with (2S,5R,6R)-6-[[3-(2,6-Dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Binotal-Diclocil; BRL 2333 / BRL 1702 Mixture
EINECS	Contact for details

Quality Control

Our Ampicillin-Dicloxacillin Mixture is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and related substances are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectra
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	90.0% - 110.0% of labeled amount of each component
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Microbial Enumeration	Meets Ph. Eur./USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.