Description

Propampicillin is a semi-synthetic penicillin derivative, specifically a prodrug of ampicillin designed for enhanced bioavailability. This compound is critical for pharmaceutical research and development, particularly in the study of antibiotic efficacy and drug delivery mechanisms. It is primarily utilized by pharmaceutical manufacturers, research institutions, and chemical suppliers serving the life sciences sector.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) for antibiotic formulations.
• Antibacterial Research: Used in microbiological and pharmacological studies to investigate the mechanisms of β-lactam antibiotics.
• Prodrug Development: Acts as a model compound in research focused on improving the oral absorption and stability of penicillin-class drugs.
• Reference Standard: Employed as an analytical standard in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.
• Chemical Synthesis: Utilized in organic synthesis for creating novel antibiotic analogs or conjugates for targeted drug delivery.

Basic Information

Product Name	Propampicillin
CAS No.	50894-67-2
Molecular Formula	C16H19N3O4S
Molecular Weight	349.41 g/mol
Synonyms	Propampicillin; Ampicillin Prodrug; D-α-Aminobenzylpenicillin Pivaloyloxymethyl Ester; Pivampicillin Hydrochloride Impurity; (2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Pivaloyloxymethyl Ester; Pivampicillin Related Compound; BRL 1341 Prodrug
EINECS	Contact for details

Quality Control

Our Propampicillin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification by IR and NMR, purity assay by HPLC, and control of specified impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.