Description

1,5-Aedans is a specialized heterocyclic organic compound widely recognized as a versatile fluorescent probe and labeling reagent in biochemical research. Its primary value lies in its ability to form stable conjugates with thiol groups, enabling sensitive detection and analysis of proteins and peptides. This makes it an essential tool for researchers and manufacturers in the fields of bioconjugation, proteomics, and diagnostic assay development. The compound is supplied with the CAS registry number 50402-62-5, ensuring precise identification for procurement and regulatory compliance.

Application

• Fluorescent Labeling of Biomolecules: Primarily used for tagging cysteine residues in proteins and peptides for fluorescence-based detection and analysis.
• Proteomics Research: Serves as a critical reagent in gel electrophoresis, Western blotting, and other techniques for protein identification and quantification.
• Diagnostic Kit Development: Employed in the formulation of fluorescent immunoassays and other clinical diagnostic tests.
• Bioconjugation Chemistry: Acts as a key intermediate for creating fluorescent antibody-drug conjugates (ADCs) or other targeted therapeutic agents.
• Cell Biology Studies: Used for intracellular labeling to track protein localization and dynamics within live or fixed cells.
• High-Throughput Screening (HTS): Utilized in assay development for drug discovery platforms that rely on fluorescence detection.

Basic Information

Product Name	1,5-Aedans
CAS No.	50402-62-5
Molecular Formula	C₁₄H₁₂N₂O₃S
Molecular Weight	288.32 g/mol
Synonyms	N-(Iodoacetyl)-N'-(5-sulfo-1-naphthyl)ethylenediamine; IAEDANS; 5-((((2-Iodoacetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid; 1,5-IAEDANS; AEDANS; Thiol-reactive fluorescent probe
EINECS	Contact for details

Quality Control

Our 1,5-Aedans is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as purity (HPLC), identity (IR, NMR), and moisture content. We adhere to cGMP principles where applicable to support our customers in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may affect performance. Keep container tightly sealed under an inert atmosphere when not in use to maximize shelf life.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water
Fluorescence Properties	Excitation ~336 nm, Emission ~490 nm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.