Description

N,N'-Dibenzylethylenediammonium [2S-(2Alpha,5Alpha,6Beta)]-Bis[3,3-Dimethyl-7-Oxo-6-[(Phenoxyacetyl)Amino]-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate] is a high-purity, non-stoichiometric salt form of the broad-spectrum antibiotic benzylpenicillin (penicillin G). This compound matters as a critical pharmaceutical intermediate and reference standard, offering enhanced stability for research, development, and quality control processes. It is primarily needed by manufacturers and R&D laboratories in the pharmaceutical and fine chemical sectors for the synthesis and analysis of penicillin-based therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key starting material or intermediate in the synthesis of penicillin G and its derivatives.
• Analytical Reference Standard: Used for quality control, method validation, and calibration in HPLC, LC-MS, and other analytical techniques within pharmaceutical laboratories.
• Microbiological Research: Employed in studies of antibiotic resistance, mechanism of action, and the development of new antimicrobial agents.
• Impurity Standard: Acts as a certified reference material for identifying and quantifying related substances in penicillin drug substances and finished products.
• Chemical Synthesis: Utilized in organic synthesis for preparing specialized penicillin analogs for structure-activity relationship (SAR) studies.
• Biochemical Reagent: Applied in enzymatic studies and as a substrate or inhibitor in various biochemical assays.

Basic Information

Product Name	N,N'-Dibenzylethylenediammonium [2S-(2Alpha,5Alpha,6Beta)]-Bis[3,3-Dimethyl-7-Oxo-6-[(Phenoxyacetyl)Amino]-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate]
CAS No.	5928-84-7
Molecular Formula	C58H64N6O10S2
Molecular Weight	1061.29 g/mol
Synonyms	Penicillin G Benzathine Salt; Benzathine Benzylpenicillin; Benzathine Penicillin G; N,N'-Dibenzylethylenediamine bis(benzylpenicillin); DBED Salt of Penicillin G; Dibenzylethylenediamine Dipenicillin G; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Deriv.; Benzylpenicillin Benzathine
EINECS	227-665-0

Quality Control

Our pharmaceutical-grade material is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency, meeting the requirements for use as a reference standard and intermediate. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting results for assay, related substances, residual solvents, and microbiological quality as applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0 %
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.