Description

Circulin A is a polypeptide antibiotic belonging to the polymyxin class, known for its potent activity against Gram-negative bacteria. This compound is critical for research and development in microbiology and pharmaceutical sciences, particularly in studying bacterial resistance mechanisms and developing novel antimicrobial agents. It serves as a valuable reference standard and active ingredient for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors.

Application

• Antimicrobial Research: Used as a reference standard in microbiological assays to study the efficacy and spectrum of polymyxin-class antibiotics.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the R&D of novel antibiotic formulations.
• Mechanistic Studies: Employed in biochemical research to investigate bacterial membrane interactions and mechanisms of action against resistant pathogens.
• Quality Control: Acts as a certified reference material (CRM) for the quality assurance and potency testing of antibiotic products.
• Academic & Institutional Use: Utilized in university and institutional laboratories for teaching and advanced research in infectious diseases.

Basic Information

Product Name	Circulin A
CAS No.	5854-98-8
Molecular Formula	C58H98N16O13
Molecular Weight	~1203.5 g/mol
Synonyms	Polymyxin P; Antibiotic 136; Circulin; Polypeptide antibiotic from B. circulans; Bacillomycin P; Bacillus circulans antibiotic
EINECS	Contact for details

Quality Control

Our Circulin A is produced and tested under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analysis including identification, potency (assay), and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Biological Potency	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.