Description

6α-[[[[2-[(Carboxymethyl)Thio]-1-Methylpropyl]Thio]Acetyl]Amino]Penicillanic Acid CAS NO 5676-16-4 is a key semi-synthetic penicillin derivative and a crucial intermediate in the synthesis of advanced β-lactam antibiotics. Its primary value lies in enabling the production of broad-spectrum antibiotics with enhanced stability and efficacy against resistant bacterial strains. This high-purity intermediate is essential for pharmaceutical manufacturers and research institutions focused on developing and producing next-generation antibacterial therapies.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of advanced penicillin and cephalosporin antibiotics.
• Antibiotic Research & Development: Serves as a key precursor for creating novel β-lactam compounds with improved pharmacological profiles.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the controlled production of specific antibiotic APIs requiring this specialized penicillanic acid structure.
• Biochemical Research: Utilized in studies exploring the structure-activity relationship (SAR) of β-lactam antibiotics and mechanisms of bacterial resistance.
• Veterinary Medicine Production: Employed in the synthesis of antibiotics for veterinary use, where specific β-lactam derivatives are required.

Basic Information

Product Name	6α-[[[[2-[(Carboxymethyl)Thio]-1-Methylpropyl]Thio]Acetyl]Amino]Penicillanic Acid
CAS No.	5676-16-4
Molecular Formula	C16H24N2O6S3
Molecular Weight	436.57 g/mol
Synonyms	6-[[[[2-[(Carboxymethyl)thio]-1-methylpropyl]thio]acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-APA derivative; Penicillanic acid derivative; (2S,5R,6R)-6-[[[[2-[(Carboxymethyl)thio]-1-methylpropyl]thio]acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Antibiotic intermediate 5676-16-4
EINECS	Contact for details

Quality Control

Our 6α-[[[[2-[(Carboxymethyl)Thio]-1-Methylpropyl]Thio]Acetyl]Amino]Penicillanic Acid is manufactured under strict quality systems suitable for pharmaceutical intermediate applications. We ensure compliance with relevant ICH guidelines and can supply material aligned with customer-specific impurity profiles. Certificates of Analysis (COA) documenting identity, purity, and related substances are provided with each batch to guarantee traceability and consistency for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.