Description

Dansyl-Methylamine is a specialized organic compound featuring a dansyl fluorophore linked to a methylamine group. This structure is critical for its primary role as a versatile derivatization and labeling reagent in analytical chemistry and biochemistry. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity reagents for sensitive detection and quantification processes. The product is supplied under strict quality control to ensure batch-to-batch consistency for demanding applications.

Application

• Fluorescent Labeling of Biomolecules: Used to tag amino acids, peptides, proteins, and amines for detection via HPLC or fluorescence spectroscopy.
• Derivatization Agent for HPLC Analysis: Enhances the detection sensitivity and selectivity of primary and secondary amines in complex matrices.
• Proteomics and Metabolomics Research: A key reagent for sample preparation and analysis in mass spectrometry and other advanced analytical platforms.
• Pharmaceutical Impurity Profiling: Employed in the identification and quantification of amine-containing impurities and degradants in drug substances.
• Bioconjugation and Probe Synthesis: Serves as a building block for creating fluorescent probes, sensors, and conjugated materials for cellular imaging.
• Quality Control in Chemical Synthesis: Acts as a reference standard or derivatizing agent to monitor reaction progress and purity in fine chemical manufacturing.

Basic Information

Product Name	Dansyl-Methylamine
CAS No.	5282-87-1
Molecular Formula	C13H16N2O2S
Molecular Weight	264.34 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonylmethylamine; Dansylmethylamine; N-Methyl-5-dimethylaminonaphthalene-1-sulfonamide; DNS-methylamine; 1-Dimethylaminonaphthalene-5-sulfonylmethylamine; Methyl(5-dimethylaminonaphthalene-1-sulfonyl)amine; N-(5-Dimethylaminonaphthalene-1-sulfonyl)methylamine
EINECS	226-104-5

Quality Control

Our Dansyl-Methylamine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and industrial applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with various pharmacopeial and industry standards, and specifications can be tailored upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.