Description

2,3,5,6-Tetrafluoro-4-Mercapto-Benzoic Acid is a highly functionalized aromatic compound featuring both a carboxylic acid and a thiol group on a perfluorinated benzene core. This unique structure makes it a valuable multifunctional building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for creating compounds with enhanced stability and specific electronic properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for advanced herbicides, fungicides, and pesticides where fluorine atoms improve metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated components for electronic display and lighting technologies.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce thiol and acid groups into specialty polymers.
• Ligand & Catalyst Design: Useful for preparing chelating ligands in coordination chemistry and catalysis.
• Surface Functionalization: Employed to modify material surfaces with specific chemical handles for further conjugation.

Basic Information

Product Name	2,3,5,6-Tetrafluoro-4-Mercapto-Benzoic Acid
CAS No.	5211-44-9
Molecular Formula	C7H2F4O2S
Molecular Weight	226.15 g/mol
Synonyms	4-Mercapto-2,3,5,6-tetrafluorobenzoic Acid; 2,3,5,6-Tetrafluoro-4-sulfanylbenzoic Acid; Tetrafluorothiosalicylic Acid; Perfluoro-4-mercaptobenzoic Acid; Benzoic acid, 2,3,5,6-tetrafluoro-4-mercapto-; 5211-44-9; 4-SH-Tetrafluorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetrafluoro-4-Mercapto-Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and titration to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.