Description

Saccharolactone is a specific lactone derivative of saccharic acid, a compound of significant interest in biochemical and pharmaceutical research. Its primary value lies in its role as a potent and specific inhibitor of the enzyme β-glucuronidase, which is crucial for modulating glucuronidation pathways. This makes it an essential research chemical for scientists and manufacturers in the pharmaceutical, diagnostic, and life science sectors, where controlling enzymatic activity is key to drug metabolism studies and assay development.

Application

• Pharmaceutical Research: Used as a standard inhibitor in studies of drug metabolism, specifically to investigate the glucuronidation pathway and the role of β-glucuronidase.
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits and assays designed to measure β-glucuronidase activity in clinical and research settings.
• Biochemical Research: Employed in enzymology studies to selectively inhibit β-glucuronidase, helping to elucidate its function in various biological processes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical and analytical laboratories.
• Microbiology: Used in specific culture media and tests for the identification of microorganisms based on β-glucuronidase activity.

Basic Information

Product Name	Saccharolactone
CAS No.	5027-63-4
Molecular Formula	C6H8O8
Molecular Weight	208.12 g/mol
Synonyms	D-Glucaro-1,4-lactone; D-Glucaric acid 1,4-lactone; D-Glucaro-1,4:6,3-dilactone; Saccharic acid 1,4-lactone; Glucarolactone; β-Glucuronidase Inhibitor; L-Gulonic acid γ-lactone (related isomer)
EINECS	225-714-7

Quality Control

Our Saccharolactone is produced and tested under a strict quality management system to ensure batch-to-batch consistency and reliability for research and production use. We offer material suitable for use as a pharmaceutical intermediate or research-grade biochemical. Comprehensive testing is performed, and a detailed Certificate of Analysis (COA) providing purity, identification, and impurity profiles is supplied with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.