Description

4-Fluoro-1-Naphthoic Acid is a versatile fluorinated aromatic carboxylic acid building block of significant importance in advanced organic synthesis. Its core value lies in the strategic introduction of both a fluorine atom and a carboxylic acid functional group onto the naphthalene scaffold, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of anti-inflammatory and anti-cancer agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated organic semiconductors and liquid crystal compounds used in electronic displays.
• Polymer & Resin Modifier: Incorporated to create specialty polymers with enhanced thermal stability, chemical resistance, and specific optical properties.
• Organic Synthesis Reagent: Utilized in coupling reactions (e.g., Suzuki, Heck) and as a precursor for other fluorinated naphthalene derivatives in academic and industrial R&D.
• Fluorescent Dye & Probe Development: Acts as a core structure for synthesizing fluorophores and molecular probes used in biochemical sensing and imaging.

Basic Information

Item	Detail
Product Name	4-Fluoro-1-Naphthoic Acid
CAS No.	573-03-5
Molecular Formula	C11H7FO2
Molecular Weight	190.17 g/mol
Synonyms	1-Naphthoic acid, 4-fluoro-; 4-Fluoronaphthalene-1-carboxylic acid; 4-Fluoro-1-naphthalenecarboxylic acid; 4-Fluoronaphthoic acid; 1-Carboxy-4-fluoronaphthalene; 4-Fluoronaphthalenecarboxylic acid; 4-Fluoro-1-naphthylcarboxylic acid; 4-Fluoronaphthalene-1-carboxylic acid
EINECS	209-350-7

Quality Control

Our 4-Fluoro-1-Naphthoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	205°C - 210°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.