Description

Methazolamide CAS NO 554-57-4 is a potent sulfonamide derivative that functions as a carbonic anhydrase inhibitor. This compound is of significant commercial and pharmaceutical importance due to its specific biological activity. It is primarily required by manufacturers in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and for research applications in medicinal chemistry.

Application

• Pharmaceutical Active Ingredient (API): Primary use as a diuretic and in the management of conditions like glaucoma and altitude sickness.
• Research & Development: Serves as a critical reference standard and building block in medicinal chemistry for developing novel carbonic anhydrase inhibitors.
• Biochemical Research: Used as a specific enzyme inhibitor in biochemical assays to study the role of carbonic anhydrase in various physiological processes.
• Veterinary Pharmaceuticals: Potential application in veterinary medicine for similar therapeutic indications.

Basic Information

Product Name	Methazolamide
CAS No.	554-57-4
Molecular Formula	C5H8N4O3S2
Molecular Weight	236.27 g/mol
Synonyms	N-(4-Methyl-2-sulfamoyl-δ²-1,3,4-thiadiazolin-5-ylidene)acetamide; 5-Acetylimino-4-methyl-δ²-1,3,4-thiadiazoline-2-sulfonamide; Methazolamid; Neptazane; Glaumet; MZM; Carbonic Anhydrase Inhibitor II
EINECS	209-066-0

Quality Control

Our Methazolamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets high-grade pharmaceutical standards. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.